Description of superfolder GFP. (A) Topological structure of superfolder GFP. The beta-strands were numbered in sequences 1 to 11, and the loops were numbered in sequences loop 1 to loop 11 (loop 5, dark gray; loop 9, light gray). (B) Side view of superfolder GFP with loop insertion site. The different loops were colored (positions 100 to 105, dark gray for loop 5; positions 171 to 176, light gray for loop 9). (C) Top view of superfolder GFP with a loop insertion site.