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. Author manuscript; available in PMC: 2015 Jun 1.
Published in final edited form as: Free Radic Biol Med. 2014 Mar 24;71:208–220. doi: 10.1016/j.freeradbiomed.2014.03.018

Fig. 6.

Fig. 6

Effect of the AMPK/Sirt1 activator resveratrol on cardiomyocyte mechanical function in young (4–5 month-old) or old (26–28 month-old) WT and ALDH2 transgenic mice. Mice were treated with resveratrol (RSV, 5 mg/kg, i.p., twice per week) for 4 weeks prior to assessment of cardiac mechanical properties. A: Resting cell length; B: Peak shortening (normalized to cell length); C: Maximal velocity of shortening (+ dL/dt); D: Maximal velocity of relengthening (− dL/dt); E: Time-to-PS (TPS); and F: Time-to-90% relengthening (TR90). Mean ± SEM, n = 70 cells per group, *p < 0.05 vs. WT-Young group, # p < 0.05 vs. WT-Old group. † p < 0.05 vs. ALDH2-Old group.