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Association of ALDH2 genetic polymorphisms with longevity in Chinese
| ALDH2 (Lys504Glu) Genetic polymorphisms |
Control (y < 90) |
Macrobian (y ≥ 90) |
Odds ratio (95% CI) |
P value |
|---|---|---|---|---|
| Normal Activity G/G) | 267/344 (77.6%) |
261/397 (65.7%) |
1 | p < 0.05 |
| Intermediate Activity (G/A) | 72/344 (20.9%) |
130/397 (32.8%) |
0.554 (0.399–0.768) |
|
| Weak Activity (A/A) | 5/344 (1.5%) |
6/397 (1.5%) |
||
| Phenotypes G | 303 88.08% |
326 82.12% |
1 | p < 0.05 |
| A | 41 11.92% |
71 17.88% |
0.621 (0.410–0.941) |
