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. 2014 Jun;50(6):1136–1143. doi: 10.1165/rcmb.2013-0357OC

Figure 4.

Figure 4.

Alt enhanced dsRNA (ds)-induced cytokine production but repressed IFN production in epithelial cells. The cells were treated with ds (25 μg/ml) and/or Alt (21.5 μg/ml) individually or in combination. Real-time PCR was used to determine the expression of proinflammatory cytokines (i.e., IL-6, IL-8) (A) and IFN-β and IFN-λ1 (C). Culture medium was collected and analyzed by ELISA for the secretions of IL-6 (B) or IFN-β (D). *P < 0.05 (n = 5) when the treated samples (Alt, ds, or ds+Alt) were compared with the control. $,&P < 0.05 (n = 5) when ds- or Alt-treated samples were compared with cotreatment (ds+Alt) samples. #P < 0.05 (n = 5) when the samples with cotreatment (ds+Alt) were compared with ds-treated samples.