Skip to main content
. 2014 Jun;50(6):1129–1135. doi: 10.1165/rcmb.2013-0434OC

Figure 1.

Figure 1.

Effect of nonmuscle myosin light chain kinase (nmMLCK) expression on airway reactivity and inflammation in a murine asthma model. (A) Airway hyperreactivity was assessed in wild-type (WT), nmMLCK−/−, and nmMLCKec/ec mice using relative airway pressure time index (APTI), a measurement of acetylcholine-induced changes in airway pressures. (B) Airway reactivity to methacholine in ovalbumin (OVA)-challenged mice. (C) Effects of nmMLCK expression on bronchoalveolar lavage (BAL) protein leakage. (D) Effects of nmMLCK expression on inflammatory leukocyte infiltration. (E–G) Effects of nmMLCK expression on Th2 cytokine secretion: IL-5 (E), IL-13 (F), and eotaxin (G) into the alveolar space (BAL) in all murine groups. *P < 0.05 compared with OVA-challenged WT mice; n ≥ 5 for all groups.