Figure 1.

Cystic fibrosis (CF) ferrets have impaired growth rates. (A) Representative pictures of CF and non-CF control ferrets between 15 days and 3 months of age. (B) Average weights of CF and non-CF control ferrets between birth and 3 months of age. Values past 5 days of age were significantly different between genotypes by two-way Student’s t test (P < 0.05). (C) Body mass index (BMI) of CF and non-CF control ferrets between birth and 3 months of age. *Values were significantly different between genotypes by two-way Student’s t test (P < 0.05). ^†The window in which pancreatic enzyme supplementation was initiated. The mechanism for the decrease in BMI of non-CF controls is unclear, although this does coincide with transition to nipple feeding and pancreatic enzyme supplementation.