Table 3.
Biomarker test# | p-value‡ | Odds Ratio (95% confidence interval) | Sensitivity | Specificity |
---|---|---|---|---|
Low IgM anti-PC/total IgM < 0.2 | 0.003 | 4.0 (1.6–10.1) | 41% | 85% |
High adiponectin > 21 ug/ml | 0.15 | 2.6 (1.0–6.5) | 30% | 83% |
High sE-selectin > 81 ng/ml | 0.06 | 2.1 (0.8–5.3) | 35% | 82% |
≥1 positive biomarker tests Low IgM anti-PC/total IgM < 0.2 High adiponectin > 21 ug/ml High sE-selectin > 81 ng/ml |
<0.0001 | 5.8 (2.4–14.2) | 77% | 64% |
Fisher’s exact test
Cutoff for positive test based on lowest quartile of anti-PC IgM/total IgM, highest quartile adiponectin, and highest quartile sE-selectin.