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. Author manuscript; available in PMC: 2015 Jul 1.
Published in final edited form as: Clin Immunol. 2014 Apr 3;153(1):1–7. doi: 10.1016/j.clim.2014.03.017

Table 3.

Predictive value of biomarker assays for presence of plaque in SLE

Biomarker test# p-value Odds Ratio (95% confidence interval) Sensitivity Specificity
Low IgM anti-PC/total IgM < 0.2 0.003 4.0 (1.6–10.1) 41% 85%
High adiponectin > 21 ug/ml 0.15 2.6 (1.0–6.5) 30% 83%
High sE-selectin > 81 ng/ml 0.06 2.1 (0.8–5.3) 35% 82%
≥1 positive biomarker tests
Low IgM anti-PC/total IgM < 0.2
High adiponectin > 21 ug/ml
High sE-selectin > 81 ng/ml
<0.0001 5.8 (2.4–14.2) 77% 64%

Fisher’s exact test

#

Cutoff for positive test based on lowest quartile of anti-PC IgM/total IgM, highest quartile adiponectin, and highest quartile sE-selectin.