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. 2014 Jun 24;9(6):e97946. doi: 10.1371/journal.pone.0097946

Figure 2. The microRNA expression in blood injection model, saline injection model, and in vitro thrombin injury model.

Figure 2

The level of let7c increased after blood injection on the same coordinate as collagenase (p = 0.0159) (A), but not after normal saline injection (p = 0.0937) (B). The in vitro thrombin injury model showed that let7c increased 24 hours after the 500 U thrombin injury (C). The let7c antagomir (AM) increased cell survival from the thrombin injury (6.38±1.09% vs. 21.89±2.01%, p = 0.037) (D). *P<0.05, n = 5–6 per group.