Table 2. Altered gene expression by Paclitaxel, TCPOBOP and their combination in E9 cells.
| Gene/Fold Change | Paclitaxel/Control | Combination/Control | TCPOBOP/Control | Function |
| Up-regulated genes | ||||
| MGMT | 54,52 | 86,2 | 3,19 | TSG |
| TO73 | 4,14 | 3,17 | 1,13 | TSG |
| RET | 4,04 | 3,43 | −1,08 | TSG&ONCO |
| ROS1 | 3,89 | 6,90 | 1,52 | ONCO |
| RASSF1 | 2,93 | 2,72 | 1,10 | TSG |
| WT1 | 2,92 | 4,19 | 2,81 | TSG |
| MOS | 2,74 | 1,57 | −1,16 | ONCO |
| ELK1 | 2,26 | 2,11 | 1,33 | ONCO |
| CASP8 | 2,26 | 2,24 | 1,21 | APOPT |
| NFKBIA | 2,03 | 1,63 | −1,41 | ONCO |
| MYCN | 1,56 | 2,25 | 1,85 | TSG&ONC |
| Down-regulated genes | ||||
| ZHX2 | −1,69 | −2,09 | −1,29 | ONCO |
| ESR1 | −1,28 | −2,16 | −1,01 | TSG&ONC |
Red values means increased gene expression by ≥2 fold. Blue values means decreased gene expression by ≤ 2 fold. TSG – Tumor suppressor gene; ONCO - Oncogene; APOPT – apoptosis-related gene