Table 2. Estimated least squares SCR means by conditioning phase and group.
Estimated means (M) and standard errors (SE) for SCR (mean amplitude in μS) for HCs and IBS patients during Acquisition, Test, and Extinction phases of the fear conditioning protocol following administration of PLA, 20 mg of the CRF-R1 antagonist, and 200 mg of the CRF-R1 antagonist.
| HC
|
IBS
|
|||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PLA
|
20
|
200
|
PLA
|
20
|
200
|
|||||||
| M | SE | M | SE | M | SE | M | SE | M | SE | M | SE | |
| Acquisition | .70 | .12 | .36 | .12 | .46 | .12 | .14 | .15 | .53 | .15 | .43 | .15 |
| Test | .40 | .10 | .49 | .10 | .41 | .09 | .39 | .12 | .42 | .12 | .38 | .12 |
| Extinction | .06 | .12 | .12 | .12 | .16 | .12 | .68 | .15 | .23 | .15 | .14 | .15 |