Table 3. Comparison of type, size and number of SNP-A abnormalities in reported APL series.
| Akagi et al. | TCGA | Nowak et al. | This Report | |
| Number of patients | n = 47 | n = 20 | n = 93 | n = 48 |
| Array type | 50 k & 250 K | SNP 6.0 | SNP 6.0 | SNP 6.0 |
| Use of germline sample | 7 (15%) | 0 (0%) | 3 (3%) | 48 (100%) |
| Patient's abnormalities | ||||
| No CNA | 28 (60%) | 13 (65%) | 16 (17%) | 25 (52%) |
| Trisomy 8/8q+ | 8 (17%) | 2 (10%) | 25 (27%) | 11 (23%) |
| Others | 11 (23%) | 5 (25%) | 52 (56%) | 12 (25%) |
| CNA types | ||||
| Duplications | 17 (50%) | 7 (54%) | 83 (32%) | 22 (48%) |
| Deletions | 10 (29%) | 6 (46%) | 171 (65%) | 23 (50%) |
| CN-LOH | 7 (21%) | 1 (5%)* | 7 (3%) | 1 (2%) |
| Total | 34 (100%) | 13 (100%) | 261 (100%) | 46 (100%) |
| CNA per case | ||||
| median | 0 | 0 | 2 | 0 |
| media | 0.72 | 0.75 | 2.78 | 0.96 |
| range | 0–4 | 0–4 | 0–14 | 0–5 |
| Size (Mb) | ||||
| median | 45.11 | 9.53 | 0.19 | 18.77 |
| media | 55.06 | 25.65 | 16.38 | 41.72 |
| range | 0.02–146.36 | 0.13–146.36 | 0.001–191.15 | 0.11–146.36 |
*one Uniparental Tetrasomy has been included both in duplication and CN-LOH group.
CNA: Copy-Number Abnormality. CN-LOH: Copy-Neutral Loss of Heterozygocity.