Table 1. Plasma hormones and metabolite levels in offspring at the age of 17 weeks.
17 Weeks | ||||
Control | BPA | HFD | HFD+BPA | |
Glucose Fasted State (mg/dL) | 121±6 | 163±13a | 190±9b | 182±7c |
Glucose (mg/dL) | 189±8 | 209±13 | 210±14 | 218±6 |
Insulin (ng/mL) | 2.0±0.3 | 3.9±0.6 | 4.0±0.9 | 3.4±0.5 |
TG (mg/mL) | 0.98±0.1 | 1.19±0.3 | 1.12±0.1 | 0.98±0.1 |
Glycerol (mg/mL) | 0.20±0.04 | 0.23±0.03 | 0.35±0.04b | 0.28±0.05 |
All measurements were performed in the fed state, otherwise stated. Fasting glucose was measured after 6 hours of fasting (n≥6 animals from ≥5 litters). Data are expressed in mean±SEM. Significance p<0.05 by one way ANOVA followed by Dunnet's method;
control vs. BPA;
control vs. HFD,
control vs. HFD-BPA.
*p<0.05 Students t-test, comparing each condition with Control and p<0.1 using Kruskal-Wallis one way ANOVA on ranks.