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. 2014 Jun 24;9(6):e100777. doi: 10.1371/journal.pone.0100777

Figure 4. Dapagliflozin suppresses inflammatory gene expression in the renal cortex.

Figure 4

Quantitative RT-PCR analysis of the expression of TGF-β (A), MCP-1 (B), osteopontin (C) and ICAM-1 (D) showed that dapagliflozin inhibited diabetes-induced inflammation in the kidney. mRNA levels were normalized against Atp5f1 expression. Data are mean ± SEM. *P<0.05.