Figure 2. Building of functional-based networks for M9 and M12 CD4+ gene expression modules using biological knowledge.

A: Functional-based network obtained from the immunologically enriched M9 gene expression module where 15 genes display a connected network. B: Functional-based network obtained from the immunologically enriched M12 gene expression module, which shows a complex network structure with different subnetworks involving 247 interconnected genes.