Table 1. Gene expression modules identified in RA CD4+ T cells.
| Module | Number of Transcripts | Immune System Process | P-value |
| M1 | 288 | NS | 3.69e-01 |
| M2 | 2326 | Underrepresented | 5.00e-03* |
| M3 | 1682 | Underrepresented | 3.41e-06* |
| M4 | 83 | Underrepresented | 1.26e-02* |
| M5 | 755 | NS | 2.64e-01 |
| M6 | 155 | NS | 3.69e-01 |
| M7 | 10003 | NS | 7.71e-01 |
| M8 | 199 | NS | 4.94e-01 |
| M9 | 75 | Overrepresented | 9.23e-21* |
| M10 | 253 | NS | 1.36e-01 |
| M11 | 157 | NS | 7.50e-01 |
| M12 | 402 | Overrepresented | 9.14e-05* |
| M13 | 124 | Underrepresented | 5.34e-23* |
| M14 | 136 | Underrepresented | 2.82e-06* |
| M15 | 2904 | NS | 7.90e-02 |
| M16 | 1578 | Underrepresented | 3.50e-05* |
Applying the new systems genetics approach for trans-eQTL identification in RA CD4+ T cells and using WGCNA, 16 genes expression modules (M) that characterize the CD4+ T cells were identified. For each gene expression module, the number of gene transcripts representing each module is shown, as well as the results of the immunological enrichment analysis.
Abbreviations: NS, No Significant.
* Significant (P<0.05).