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(A) Cytotoxicity in HEK-293 cells exposed to CSO-SA and CA-CSO-SA micelles at various concentrations and incubated for 48 hours. (B) Cell viability was measured for CA-CSO-SA/pDNA and CA-CSO-SA/pDNA nanocomplexes at different weight ratios.
Notes: n=3, error bars represent the standard deviation. Lipofectamine™ (Invitrogen Corporation, Carlsbad, CA, USA).
Abbreviations: CA, cis-aconitate; SA, stearic acid; CSO, chitosan oligosaccharide; pDNA, plasmid DNA; Lipo, Lipofectamine™.
