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The time course of elemental platinum concentrations in the plasma (A) and tumor (B), after intravenous administration of oxaliplatin (4 mg/kg) or NC-4016 (an equivalent dose to 4 mg/kg).
Notes: Each drug was administered to KB-bearing nude mice (female, n=4). Data are presented as mean ± SEM.
Abbreviation: SEM, standard error of the mean.
