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. 2014 Jun 24;9(6):e100838. doi: 10.1371/journal.pone.0100838

Figure 5. Histological assessment of joint inflammation.

Figure 5

A. Histology of the radio-carpal joint for CMC control group at day 63. B. Histology of the radio-carpal joint for ECR527 & EA group at day 63. C. Histology of the radio-carpal joint for W50 & EA group at day 63. Arows indicate increased inflamaotry reaction in joint. D. Histological scores (mean ± SEM) for (a) inflammation and (b) bone and cartilage destruction for both front and rear paws combined. Original magnification of A–C = 100X. The number of animals in each group was 6 and measurements were performed in triplicate. Statistical analysis was done by One way ANOVA and Bonferroni multiple comparisons. Abbreviations: CMC = carboxymethyl cellulose; ECR527 = PAD-deficient P. gingivalis; W50 = wild type P. Gingivalis; EA = experimental arthritis