Table 2.

Multivariable-adjusted^a linear regression coefficients (β) for the association of log-transformed IL-6, TNF-α and CRP with BMD of the hip and spine among men of the Framingham Offspring cohort.

	Neck		Trochanter		Total Femur		Lumbar spine
	β b	P-value	β	P-value	β	P-value	β	P-value
IL-6 (pg/mL)	0.003	0.57	−0.002	0.67	0.001	0.86	0.009	0.28
TNF-α (pg/mL)	−0.004	0.64	−0.012	0.22	−0.009	0.35	−0.014	0.33
CRP (mg/L)	−0.006	0.11	−0.005	0.20	−0.005	0.22	−0.007	0.24

^aModels adjusted for age, BMI, height, physical activity (PASE) and smoking

^bDifference in BMD for each 1 unit increase in log-transformed IL-6, TNF-α or CRP