Table 2.
Progression Categories for Coronary Artery Calcium (CAC) and Aorta Calcium (AC) in Women with SLE (cases) and Controls from the Study of Lupus Vascular and Bone Long-term Endpoints (2002-present), Chicago, IL
Low without Progression (N(%)) | Low with Progression (N(%)) | High to Low (N(%)) | High without Progression (N(%)) | High with Progression (N(%)) | Relative Risk (95% CI) | ||
---|---|---|---|---|---|---|---|
CAC | Cases (N=149) | 106 (71.1) | 14 (9.4) | 2 (1.3) | 14 (9.4) | 13 (8.7) | 1.77 (1.03–3.05) |
Controls (N=124) | 101 (81.5) | 10 (8.1) | 3 (2.4) | 4 (3.2) | 6 (4.8) | ||
AC | Cases (N=113) | 71 (62.8) | 15 (13.3) | 4 (3.5) | 6 (5.3) | 17 (15.0) | 1.57 (0.97–2.53) |
Controls (N=122) | 88 (72.1) | 10 (8.2) | 2 (1.6) | 10 (8.2) | 12 (9.8) |
Low CAC defined as < 10 Agatston units, low AC defined as < 100 Agatston units. High CAC defined as ≥ 10 Agatston units, high AC defined as ≥ 100 Agatston units.
Progression definition:
If CAC = 0 Agatston units at baseline, progression was defined as CAC > 0 Agatston units at follow-up. If 0 < CAC < 100 Agatston units at baseline, progression was defined as an annualized change of ≥ 10 Agatston units at follow-up. If CAC ≥ 100 Agatston units at baseline, progression was defined as an annualized percent change ≥ 10% at follow-up. If AC = 0 Agatston units at baseline, progression was defined as AC > 0 Agatston units at follow-up. If 0 < AC < 1000 Agatston units at baseline, progression was defined as an annualized change of ≥ 100 Agatston units at follow-up. If AC ≥ 100 Agatston units at baseline, progression was defined as an annualized percent change ≥ 10% at follow-up.
Relative Risks were calculated as the ratio of the proportion of all cases who progressed and the proportion of all controls who progressed.