Table 3.
Statistical associations between allele frequencies and a set of three explanatory variables (TEMP, temperature; LAT, latitude; LON, longitude) assessed using generalized linear models (GLM) and BAYENV based on the full data set with 8 locations (78 loci) and a reduced data set with 7 locations (80 loci)
|
GLM |
|
|
|---|---|---|
| Locus | Gene | p value |
|
8 populations |
|
|
| TRIM_35_8416 |
Tripartite motif-containing protein 35 |
TEMP (r = 0.78; p = 0.023) |
| NEX_19953 |
Nexilin |
LAT (r = 0.80; p = 0.018) |
| GAPDH_20355 |
Glyceraldehyde-3-phosphate dehydrogenase |
LAT (r = 0.72; p = 0.045) + LON (r = 0.74; p = 0.042) |
| KRT_13_20618 |
Keratin |
TEMP (r = 0.81; p = 0.015) |
| UBI_A52_5049 |
Ubiquitin A-52 |
LON (r = 0.72; p = 0.044) |
| PGK_1_11454 |
Phosphoglycerate kinase |
LON (r = 0.76; p = 0.031) |
| PSA_4_21534 |
Proteasome subunit alpha type-4 |
LAT (r = 0.80; p = 0.018) |
| ALDH_2_16634 |
Aldehyde dehydrogenase 2 |
LON (r = 0.72; p = 0.044) |
| CST_21113 |
Cystatin precursor |
LON (r = 0.72 p = 0.043) |
|
7 populations |
|
|
| TRIM_35_8416 |
Tripartite motif-containing protein 35 |
TEMP (r = 0.77; p = 0.042) |
| NEX_19953 |
Nexilin |
LAT (r = 0.76; p = 0.045) |
| GAPDH_20355 |
Glyceraldehyde-3-phosphate dehydrogenase |
LON (r = 0.73; p = 0.046) |
| KRT_13_20618 |
Keratin |
TEMP (r = 0.82; p = 0.023) |
| PSA_4_21534 |
Proteasome subunit alpha type-4 |
LAT (r = 0.76; p = 0.047) |
| ALD_R |
Aldose reductase |
LON (r = 0.82; p = 0.016) |
|
BAYENV |
|
|
|
Locus |
Gene |
BF |
|
8 populations |
|
|
| GAPDH_20355 |
Glyceraldehyde-3-phosphate dehydrogenase |
LAT (BF = 7.450) |
|
7 populations |
|
|
| GAPDH_20355 |
Glyceraldehyde-3-phosphate dehydrogenase |
LAT (BF = 4.501) |
| ALD_R | Aldose reductase | LON (BF = 3.295) |
Correlation coefficients and p-values are detailed for all loci showing significant associations using GLM. Bayes Factors (BF) are presented for all positive associations in BAYENV.