Area under receiver operating characteristic curve (AUROC) |
The AUROC is a measure of how well a parameter can distinguish between two diagnostic groups (diseased/normal) |
Accuracy |
Consists of Trueness (proximity of measurement results to the true value) and Precision (repeatability or reproducibility of the measurement) |
Negative predictive value |
Proportion of people with a negative test who are free of the target disorder |
Positive predictive value |
Proportion of people with a positive test who have the target disorder |
Sensitivity |
Proportion of people with the target disorder who have a positive test result |
Specificity |
Proportion of people without the target disorder who have a negative test |
Imaging techniques |
Ultrasonography-based transient elastography (FibroScan) |
Technique whereby shear waves, at a low frequency of 50 Hz, are created by a vibrating probe and transducer applied to the skin overlying the liver |
Acoustic radiation force impulse |
Use of shear acoustic waves remotely induced by the radiation force of a focused ultrasonic beam |
Magnetic resonance imaging-based Proton magnetic resonance spectroscopy |
Quantifies hepatosteatosis by measuring proton signals from the acyl groups of hepatocyte triglyceride stores |
Magnetic resonance elastography |
Obtained by depicting the propagated shear waves, and images of the shear waves are analyzed and used to generate the elastogram |