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. 2014 Apr 9;31(7):1894–1901. doi: 10.1093/molbev/msu129

Table 1.

Parsimony Approaches Scoring Motifs as Present/Absent Undercount Losses.

Data Set Species Surveyed Gains Losses
Meunier et al. (2013)a Human, macaque, mouse, oppossum, platypus, chicken 719 140
Nozawa et al. (2010)a (Drosophila) melanogaster, simulans, sechellia, yakuba, erecta, ananassae, pseudoobscura, persimilis, willistoni, mojavensis, virilis, grimshawi 101 48
Nozawa et al. (2012)a Arabidopsis, papaya, poplar, Medicago, soybean, grape, rice, Sorghum, maize, moss, green algae 743 77
Xiao et al. (2013)a Oryza Sativa, Phoenix Dactylifera, Populus Trichocarpa, Malus domestica, Glycine max, Solanum lycopersicum, Citrus sinensis, Arabidopsis thaliana 167 4
Current study, experimental primate parsimonyb Human, chimp, gorilla, orangutan, gibbon 8,337,944 6,087,687
Current study, simulated neutral primate parsimonyc Human, chimp, gorilla, orangutan, gibbon 11,829 8,806

aEarlier studies examining the turnover rates of miRNA genes find many more gain events than losses.

bWhen using these methods, more gains than losses are inferred for the turnover rates of miRNA binding sites in the 3′-UTRs of primates.

cSimulated neutral data sets (which have been simulated to have identical gain and loss rates in reality) also infer more gains than losses.