Figure 1.

Population dynamics of P. minimum and D. shibae in co-culture. (A) Experimental setup of the co-cultivation experiment. (B) Growth of P. minimum and D. shibae determined by flow cytometric analysis. In the mutualistic phase (day 0–day 21) both organisms profit from the co-cultivation in a medium where single organisms are not able to grow. In the pathogenic phase (day 21–day 36) the algae are killed by the bacteria, which continue to grow. The red arrow indicates the sampling time point. Data represent mean and standard deviation of three biological replicates.