Table 3.
Comparison of GST genotypes frequencies between T2DM and control groups
| Controls (n=201) n% | T2DM (n=404) n (%) | OR a | 95% CI b | P value c | |
|---|---|---|---|---|---|
| GSTM1 | |||||
| Present | 103(51.2) | 171 (42.3) | 1 (reference) | --- | --- |
| null | 98(48.8) | 233 (57.7) | 1.43 | 1.01-2.04 | 0.03 |
| GSTT1 | |||||
| Present | 161 (72.9) | 299 (75.1) | 1 (reference) | --- | --- |
| null | 40 (27.1) | 105 (24.9) | 1.41 | 0.92-2.18 | 0.09 |
| GSTM1-present/GSTT1-present | 86 (42.8) | 133 (32.9) | 1 (reference) | --- | --- |
| GSTM1-present/GSTT1-null | 17 (8.5) | 38 (9.4) | 1.45 | 0.74-2.86 | 0.25 |
| GSTM1-null/GSTT1-present | 75 (37.3) | 166 (41.1) | 1.43 | 0.96-2.14 | 0.07 |
| GSTM1-null/GSTT1-null | 23 (11.4) | 67 (16.6) | 1.88 | 1.06-3.38 | 0.02 |
a
Odds ratio
b
Confidence interval from conditional logistic regression analysis
C
Significant differences between groups (P < 0.05)