Table 4.

C677T and A1298C genotypes and risk of CML

Polymorphism			Cases (N = 85)		Control (N = 100)		OR	95% CI		P
			N.	%	N.	%
C677T	Genotype	CC	30	35.2	45	45.0	1	-	-	-
		CT	44	51.7	49	49.0	1.010	0.460	2.218	0.981
		TT	11	12.9	6	6.0	2.513	0.722	4.086	0.025
	Allele	C	64	75.9	75	75.0	0.786	0.429	1.442	0.436
		T	21	24.7	25	25.0
A1298C	Genotype	AA	32	37.6	40	40.0	1	-	-	-
		AC	38	44.7	51	51.0	1.046	0.740	1.759	0.092
		CC	15	17.6	9	9.0	1.816	0.952	3.573	0.036
	Allele	A	56	65.8	68	68.0	0.827	0.490	1.398	0.478
		C	29	34.1	32	32.0
C677T/A1298C		CC/AA	11	12.9	36	36.0	0.470	0.264	0.738	0.562
		CC/AC	14	16.4	19	19.0	1.258	0.547	1.052	0.937
		CC/CC	10	11.7	5	5.0	0.694	0.452	0.939	0.583
		CT/AA	18	21.1	13	13.0	1.050	0.853	2.059	0.459
		CT/AC	26	30.5	24	24.0	1.849	0.935	2.540	0.024
		TT/AA	4	4.7	2	2.0	1.204	0.895	1.630	0.095
		TT/CC	2	2.3	1	1.0	1.915	1.202	3.845	0.020