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. 2014 Apr 15;7(5):2179–2184.

Figure 5.

Figure 5

ADGB knockdown altered levels of proteins related to proliferation, survival or apoptosis in U251 cells. A. Western blot showed that ADGB knockdown decreased the phosphorylated levels of STAT3 and Akt. B. Grayscale ratios of STAT3/GAPDH or Akt/GAPDH revealed that the expression levels of STAT3 and Akt were not changed in ADGB knockdown group. Grayscale ratios of P-STAT3/STAT3 and P-Akt/Akt reveald that the phosphorylated levels of STAT3 and Akt were decreased in ADGB knockdown group. C. ADGB knockdown also decreased the expression level of Cyclin D1, Bcl-2 and increased the expression level of cleaved caspase-3. GAPDH was sample loading control.