Table 1.
Association between miR-200a, miR-200b, miR-200c expression and clinicopathological characteristics of epithelial ovarian cancer
| Factor | Cases no. | miR-200a expression | P | miR-200b expression | P | miR-200c expression | P |
|---|---|---|---|---|---|---|---|
|
|
|
|
|||||
| High (n, %) | High (n, %) | High (n, %) | |||||
| Age (year) | |||||||
| <58 | 58 | 31 (53.45) | NS | 30 (51.72) | NS | 31 (53.45) | |
| ≥58 | 42 | 22 (52.38) | 20 (47.62) | 21 (50.00) | |||
| FIGO stage | |||||||
| I~II | 56 | 17 (30.35) | 0.006 | 14 (25.00) | 0.006 | 20 (35.71) | 0.01 |
| III~IV | 44 | 36 (81.82) | 36 (81.82) | 32 (72.73) | |||
| Histologic type | |||||||
| Serous carcinoma | 60 | 36 (60.00) | NS | 36 (60.00) | NS | 36 (60.00) | NS |
| Mucinous carcinoma | 13 | 9 (69.23) | 6 (46.15) | 8 (61.54) | |||
| Endometrioid carcinoma | 15 | 5 (33.33) | 5 (33.33) | 5 (33.33) | |||
| Clear cell carcinoma | 10 | 2 (20.0) | 2 (20.0) | 2 (20.0) | |||
| Others | 2 | 1 (50.00) | 1 (50.00) | 1 (50.00) | |||
| Histologic grade | |||||||
| Grade 1 | 23 | 7 (30.43) | 0.01 | 7 (30.43) | 0.02 | 11 (47.83) | NS |
| Grade 2 | 29 | 13 (44.83) | 13 (44.83) | 11 (37.93) | |||
| Grade 3 | 48 | 33 (68.75) | 30 (62.50) | 30 (62.50) | |||
| Residual tumor size | |||||||
| <1 cm | 64 | 30 (46.88) | NS | 30 (46.88) | NS | 30 (46.88) | NS |
| ≥1 cm | 36 | 23 (63.89) | 20 (55.56) | 22 (61.11) | |||
| Chemoresistance | |||||||
| Yes | 37 | 24 (64.86) | NS | 21 (56.76) | NS | 23 (62.16) | NS |
| No | 63 | 29 (46.03) | 29 (46.03) | 29 (46.03) | |||
| Recurrence | |||||||
| Yes | 54 | 30 (55.56) | NS | 27 (50.00) | NS | 29 (53.70) | NS |
| No | 46 | 23 (50.00) | 23 (50.00) | 23 (50.00) |