Figure 1.

Apelin expression in chronic hepatitis and liver cirrhosis: (A) Chronic hepatitis showing Apelin expression in hepatic stellate cells (HSC) with exemption of fibrotic septa and hepatocytes, (B) In Metavir F1, Apelin was slightly expressed, (C) In F3, there was significant increase in Apelin positive HSC, (D, E) In cirrhosis, Apelin extended as linear staining in the cirrhotic septa and proliferated capillaries, (F) Apelin expressed in hepatocytes exhibiting steatosis. [Immunohistochemistry, original magnification, (A) × 200; (B, C, E, F) × 400, (D) × 100].