Table 1.
Apelin expression in normal liver, chronic hepatitis and cirrhosis
| Tissue sample | n | Apelin expression in | |||||
|---|---|---|---|---|---|---|---|
|
| |||||||
| Non-parenchymatous cells | P valuea | Hepatocytes | P valuea | ||||
|
|
|
||||||
| Mean ± SD | Median | Mean ± SD | Median | ||||
| Normal lver | 5 | 0 ± 0.0 | 0 | < 0.001 | 0 ± 0.0 | 0 | 0.58 |
| Chronic hepatitis | 43 | 0.419 ± 0.54 | 0 | 0.23 ± 0.427 | 0 | ||
| Cirrhosis | 18 | 2.5 ± 1.2 | 3 | 0.11 ± 0.32 | 0 | ||
Non-parenchymatous cells: sinusoidal endothelial cells/hepatic stellate cells, myofibroblasts, endothelial cells.
a
P value presents the differences between the three groups.
Apelin in non-parenchymatous cells & hepatocytes in: Cirrhosis versus normal, P = 0.001 & 0.446, respectively. Cirrhosis versus chronic hepatitis, P < 0.001 & 0.22, respectively. Chronic hepatitis versus normal, P = 0.08 & 0.2, respectively. Significant P-values are in bold.