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. 2014 Apr 15;7(5):1947–1956.

Figure 3.

Figure 3

CREB activity is reduced in OA chondrocytes. CREB luciferase reporter gene assays were performed comparing normal chondrocytes to chondrocytes derived from OA patients. A significant difference in CREB activity was observed comparing normal and OA chondrocytes, whereas NFkB signaling was unchanged. (***: p < 0.001; ns: p > 0.05)