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. 2014 Apr 15;7(5):2595–2608.

Figure 1.

Figure 1

HSYA pretreatment attenuates hepatic I/R injury. Serum transaminase ALT (A) and AST (B) levels in sham-operated mice (n = 5 per group) or mice pretreated with vehicle or HSYA (5 or 15 mg/kg, n = 5-8 per group) prior to 90 min of hepatic ischemia followed by 2, 6, or 24 hours of reperfusion. (C) Representative histopathologic images of ischemic liver lobes at 6 or 24 hours after reperfusion. H&E staining with original magnification ×100, bar equals 200 μm. (D) Quantification of necrotic areas. A minimum of 10 view fields per animal was included. *P < 0.05 vs. vehicle–sham group; #P < 0.05 vs. corresponding control exposed to vehicle-I/R.