Table 1.
Correlation of clinicopathologic parameters with overexpression of HER2 (3+ staining)
| Clinicopathologic data | Breakdown of cases with HER2 | Total number of cases with HER2 overexpression (%) |
|---|---|---|
| Male | 28 | 34a (82%) |
| Female | 6 | 34 (18%) |
| High grade UCA | 32 | 34 (94%) |
| Low grade UCA | 2 | 34 (6%) |
| pTa | 9 | 34 (26%) |
| pT1 | 10 | 34 (29%) |
| pT2 | 2 | 34 (6%) |
| pT3 | 12 | 34 (35%) |
| pT4 | 1 | 34 (3%) |
| Inverted growth pattern | 15 | 23b (65%) |
a
34/46 (74%) cases had HER2 overexpression (3+ staining);
b
23/46 (50%) cases had an inverted growth pattern;
UCA: urothelial carcinoma.