Table 1.
Tumor grade in dysplasia and carcinoma of the gastric mucosa and IMP3/p53 immunohistochemistry
| Category | IMP3 product score | P53 | ||||
|---|---|---|---|---|---|---|
|
|
||||||
| N | Positive (%) | Negative (%) | Positive (%) | Negative (%) | ||
| Low grade dysplasia of the gastric mucosa | 16 | 0 (0) | 16 (100) | 2 (13) | 14 (87) | |
| High grade dysplasia of the gastric mucosa | 12 | 10 (83) | 2 (17) | 7 (58) | 5 (42) | |
| Low grade vs. high grade dysplasia of the gastric mucosa | Fisher Test: p = 5.0-06 | Fisher Test: p = 0.017 | ||||
| Invasive gastric adenocarcinoma, both diffuse and intestinal type | All grades | 63 | 41 (65) | 22 (35) | 29 (46) | 35 (56) |
| G1 | 5 | 4 (80) | 1 (20) | 1 (20) | 4 (80) | |
| G2 | 16 | 13 (81) | 3 (19) | 10 (63) | 6 (37) | |
| G3 | 42 | 24 (57) | 18 (43) | 17 (40) | 25 (60) | |
| Armitage Trend Test: p = 0.10 | Armitage Trend Test: p = 0.93 | |||||
| Invasive gastric adenocarcinoma, intestinal type | All grades | 33 | 26 (77) | 8 (24) | 13 (40) | 20 (60) |
| G1 | 5 | 4 (80) | 1 (20) | 1 (20) | 4 (80) | |
| G2 | 16 | 13 (81) | 3 (19) | 10 (63) | 6 (37) | |
| G3 | 12 | 8 (67) | 4 (33) | 2 (17) | 10 (83) | |
| Armitage Trend Test: p = 0.52 | Armitage Trend Test: p = 0.52 | |||||
| Invasive gastric adenocarcinoma, diffuse type | All grades | 30 | 16 (53) | 14 (47) | 15 (50) | 15 (50) |
| G3 | 30 | 16 (53) | 14 (47) | 15 (50) | 15 (50) | |