Table 1.

MicroRNAs downregulated in GBC tissues

miRCode	Log(2) Fold-Changea	Chromosomal location
hsa-miR-133a; hsa-miR-133b	-3.58	18q11.2 (a-1); 20q13.33 (a-2); 6p12.2 (b)
hsa-miR-143-3p	-3.18	5q32
hsa-miR-145-5p	-2.81	5q32
hsa-miR-99a-5p	-2.52	21q21.1
hsa-miR-125b-5p	-2.46	11q24.1 (b-1); 21q21.1 (b-2)
hsa-miR-1	-2.03	20q13.33 (-1); 18q11.2 (-2)
hsa-miR-29c-3p	-1.98	1q32.2
hsa-miR-195-5p	-1.86	17p13.1
hsa-miR-139-5p	-1.74	11q13.4
hsa-miR-29c-5p	-1.61	1q32.2
hsa-miR-100-5p	-1.58	11q24.1
hsa-miR-143-5p	-1.53	5q32
hsa-miR-148a-3p	-1.42	7p15.2
hsa-miR-145-3p	-1.32	5q32
hsa-miR-376c	-1.29	14q32.31
hsa-miR-187-3p	-1.27	18q12.2
hsa-miR-365a-3p	-1.24	16p13.12 (a); 17q11.2 (b)
hsa-miR-29b-3p	-1.24	7q32.3 (b-1); 1q32.2 (b-2)
hsa-miR-497-5p	-1.20	17p13.1
hsa-miR-654-3p	-1.20	14q32.31
hsa-miR-411-5p	-1.12	14q32.31
hsa-miR-125a-5p	-1.10	19q13.41
hsa-miR-26a-5p	-1.09	3p22.2 (a-1); 12q14.1 (a-2)
hsa-miR-101-3p	-1.08	1p31.3 (-1); 9p24.1 (-2)
hsa-miR-495	-1.05	14q32.31
hsa-miR-381-3p	-1.00	14q32.31
hsa-miR-154-5p	-0.96	14q32.31
hsa-miR-99a-3p	-0.88	21q21.1
hsa-miR-328	-0.87	16q22.1
hsa-miR-299-5p	-0.85	14q32.31
hsa-miR-30e-3p	-0.83	1p34.2
hsa-miR-29b-2-5p	-0.80	1q32.2
hsa-miR-379-5p	-0.76	14q32.31
hsa-miR-140-5p	-0.74	16q22.1
hsa-miR-24-1-5p	-0.59	9q22.32
hsa-miR-101-5p	-0.49	1p31.3

^aFold changes were calculated by comparison of the mean expression value in the tumor group to the control group (normal gallbladder tissues).