Table 3.
Univariate and multivariate analyses of prognostic parameters in 40 patients with Kimura’s disease by Cox-regression analysis
| Variable | Univariate analysis | Multivariate analysis | ||||
|---|---|---|---|---|---|---|
|
| ||||||
| Hazard ratios | 95% CI | P-values | Hazard ratios | 95% CI | P-values | |
| Age (< 35/≥ 35) | 1.387 | 0.404-4.767 | 0.604 | - | - | - |
| Gender (male/female) | 0.042 | 0.000-412.779 | 0.500 | - | - | - |
| Initial location (head and neck/others) | 0.424 | 0.054-3.346 | 0.416 | - | - | - |
| Multiplicity (single/multiple) | 3.932 | 0.501-30.888 | 0.193 | - | - | - |
| Laterality (unilateral/bilateral) | 1.006 | 0.127-7.985 | 0.995 | - | - | - |
| Peripheral eosinophils (< 20%/20%-35%/≥ 35%) | 3.595 | 1.567-8.248 | 0.003* | 718.810 | 4.282-1.207 × 105 | 0.012* |
| Largest mass sizes (< 3.5/≥ 3.5) | 5.883 | 1.534-22.565 | 0.010* | 3.519 | 0.639-19.381 | 0.148 |
| Notch-1 expression (-/+/++) | 2.939 | 1.020-8.467 | 0.046* | 31.848 | 2.258-449.207 | 0.010* |
| Ki-67 proliferation index (< 3%/≥ 3%) | 9.918 | 1.256-78.323 | 0.030* | 448.684 | 3.129-6.433 × 104 | 0.016* |