Table 1.
Correlation between Nek2 protein expression and clinicopathologic features in PDA Patients
| Variables | Nek2 | χ2 | P-value | |
|---|---|---|---|---|
|
| ||||
| Low | High | |||
| Gender | ||||
| Male | 28 (38.9) | 44 (61.1) | 2.768 | 0.096 |
| Female | 34 (53.1) | 30 (46.9) | ||
| Age (years) | ||||
| <60 | 25 (49.0) | 26 (51.0) | 0.387 | 0.534 |
| ≥60 | 37 (43.5) | 48 (56.5) | ||
| Tumor location | ||||
| Head | 28 (41.8) | 39 (58.2) | 0.768 | 0.381 |
| Body/tail | 34 (49.3) | 35 (50.7) | ||
| Histological differentiation | ||||
| Well/moderately | 41 (55.4) | 33 (44.6) | 6.307 | 0.012 |
| Poorly | 21 (33.9) | 41 (66.1) | ||
| Lymph node metastasis | ||||
| Present | 30 (36.6) | 52 (63.4) | 6.748 | 0.009 |
| Absent | 32 (59.3) | 22 (40.7) | ||
| Clinical stage (pTNM) | ||||
| Early stage (I-II) | 37 (54.4) | 31 (45.6) | 4.269 | 0.039 |
| Advanced stage (III-IV) | 25 (36.8) | 43 (63.2) | ||
| Respectability | ||||
| RR | 54 (49.5) | 55 (50.5) | 3.459 | 0.063 |
| PR | 8 (29.6) | 19 (70.4) | ||
Bold values indicate P<0.05. RR indicates radical resection; PR indicates palliative resection.