Figure 1.

The distribution of nestin-positive cells. The distribution of nestin-positive cells. At 6 h after establishment of the acute pancreatitis model, nestin-positive cells were concentrated in the walls of the interlobar vessels. Tissue cross-sections showed that nestin-positive cells were arranged in a circular manner along the vessel walls. Nestin-positive cells (Arrow) were also observed in the lumen of certain interlobar vessels (A). At 1 d after the establishment of pancreatitis, nestin-positive cells had migrated along the interlobar vessels toward the pancreatic lobules. A portion of the nestin-positive cells was also distributed along the walls of interlobar vessels in 2 parallel lines (Arrow), and a few nestin-positive cells were scattered in the pancreatic acinar and islet tissues (B, C). At 2 d, the number of scattered nestin-positive cells in the pancreatic lobules had increased significantly. In addition, nestin-positive cells gathered in the pancreatic islets (Arrow). A portion of the nestin-positive cells remained distributed along the interlobar vessels (D).