Table.
Baseline characteristics of 8 children presenting with profound primary hypothyroidism and PsPP
| Pt | Sex | Reason for lab draw/referral |
Symptoms exposed by medical doctor |
CA(y) | BA (y) | BA-SDS | Height- SDS |
Weight- SDS |
BMI- SDS |
Goiter | Breast stage* |
PH stage |
Vaginal bleed |
Testes volume |
TSH (mIU/L) |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | F | Vaginal bleeding | 6.8 | 4.2 | −3.8 | −0.9 | 1.6 | 2.3 | N | 2 | 1 | Y | 2632 | ||
| 2 | F | Fatigue, constipation | 10.1 | 6.8 | −3.7 | −1.2 | −0.7 | 0.1 | Y | 2 | 1 | N | >600 | ||
| 3 | F | LENG | Vaginal bleeding | 10.8 | 7.0 | −3.7 | −1.9 | 0.5 | 1.7 | N | 4 | 1 | Y × 1 | 648 | |
| 4 | F | LENG | 11.2 | 7.8 | −4.1 | −2.3 | 0.2 | 1.6 | N | 3 | 1 | N | 814 | ||
| 5 | F | LENG | Vaginal bleeding | 11.2 | 7.0 | −3.3 | −1.4 | −0.2 | 0.8 | N | 3 | 1 | Y × 2 | 11 553 | |
| 6 | F | Weight gain, fatigue | Vaginal bleeding, galactorrhea |
14.3 | 8.0 | −6.0 | −4.6 | 0.4 | 2.0 | N | 1 | 2 | Y × 3 | 430 | |
| 7 | M | LENG | 4.3 | 1.3 | −13.5 | −4.6 | −2.0 | 2.0 | N | 1 | 1 | 4mL | 967 | ||
| 8 | M | LENG | 13.3 | 7.0 | −6.8 | −3.8 | −2.2 | 0.4 | N | 1 | 2 | 8mL | >170 |
F, female; LENG, lack of expected normal growth; M, male; N, no (not present); PH, pubic hair Tanner stage; Pt, patient; Y, yes (present).
*
Breast stage = breast Tanner stage.