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. 2014 Jun 25;5:166. doi: 10.3389/fgene.2014.00166

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Copyright © 2014 Kullo, Shameer, Jouni, Lesnick, Pathak, Chute and de Andrade.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Manhattan plot for the Stage I discovery cohort showing genome wide P-value distribution and the corresponding Q-Q plot (inset). SNP rs653178 is circled. A line at p = 1 × 10⁻⁴ is included on the Manhattan plot to provide a visual reference for p-values across the chromosomes.