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Estimated Simple Physiological Model Parameters for the Population
| Parameter (unit) | Population mean final estimate (%CV) | Inter-individual variance final estimate (%CV) |
|---|---|---|
| Volume of central compartment, V c, (L) | 3.8 (7.3) | 33.9 (29.1) |
| k Cen ‐ Per (day)−1 | 0.36 (16.87) | 17.1 (30.2) |
| k LN (day)−1 | 0.51 (16.09) | 43.6 (31.6) |
| k EL (day)−1 | 0.044 (3.9) | 22.8 (30.7) |
| Model AIC | 5,796 |
