Table 3.
Comparison between patients with secondary renal outcome and those without
| Variables | Renal outcome (-) | Renal outcome (+) | P –value |
|---|---|---|---|
| N |
104 |
14 |
|
| Age at the time of biopsy (years) |
26 (19–37) |
27 (25–35) |
0.640 |
| Sex (male, %) |
47/104 (45.2%) |
3/14 (21.4%) |
0.148 |
| Body mass index (kg/m2) |
21.6 (19.9–23.5) |
21.7 (20.5–23.1) |
0.749 |
| Systolic blood pressure (mmHg) |
120 (110–126) |
115 (110–130) |
0.990 |
| Serum creatinine (mg/dL) |
0.90 (0.80–1.04) |
0.80 (0.70–0.90) |
0.016 |
| eGFR (ml/min/1.73 m2) |
86.4 (74.9–105.6) |
93.0 (82.5–113.2) |
0.142 |
| Albumin (g/dL) |
4.1 (3.9–4.4) |
3.9 (3.5–4.3) |
0.038 |
| Proteinuria (g/day) |
0.25 (0.10–0.40) |
0.28 (0.10–0.41) |
0.680 |
| WHO grade |
2.0 (2.0–2.0) |
2.5 (2.0–3.0) |
0.047 |
| Global sclerosis ≥ 10% |
32/104 (30.8%) |
8/14 (57.1%) |
0.214 |
| Segmental sclerosis ≥ 10% |
9/104 (8.7%) |
5/14 (35.7%) |
0.012 |
| Cresent |
10/104 (9.6%) |
1/14 (7.1%) |
1.000 |
| Mesangial proliferation |
15/103 (14.6%) |
3/14 (21.4%) |
0.450 |
| Interstitial fibrosis |
8/103 (7.8%) |
5/14 (35.7%) |
0.009 |
| Interstitial inflammation |
1/103 (1.0%) |
0/14 (0.0%) |
1.000 |
| Tubular atrophy |
11/103 (10.7%) |
5/14 (35.7%) |
0.024 |
| RAS blockade (N, %) | 48/103 (45.4%) | 12/14 (84.6%) | 0.009 |