Table 2.

Main results of meta-analysis according to the different cutoff values of ALDH1A1expression

Parameter	Cutoff value				Patients’ district				Patients’ stage
	5%		0% or 1%		America-Europe		Asia		NA		≥Stage II
	OR/HR	95% CI	OR/HR	95% CI	OR/HR	95% CI	OR/HR	95% CI	OR/HR	95% CI	OR/HR	95% CI
Tumor size	1.30	0.92-1.83	1.29*	1.01-1.65	1.24	0.95-1.61	1.37*	1.01-1.86	1.31*	1.06-1.62	1.19	0.66-2.14
LNM	1.43	0.99-2.07	1.20	0.94-1.54	1.33*	1.03-1.72	1.16	0.82-1.64	1.27*	1.03-1.56	1.29	0.33-4.97
SBR grade	2.33*	1.22-4.43	2.32*	1.20-4.49	2.16*	1.31-3.55	2.41*	1.16-5.04	2.37*	1.57-3.58	2.94	0.80-10.77
ER	0.46*	0.34-0.61	0.43*	0.33-0.55	0.47*	0.36-0.61	0.42*	0.32-0.54	0.41*	0.33-0.50	0.54*	0.36-0.82
PR	0.54*	0.30-0.98	0.46*	0.25-0.84	0.56*	0.33-0.96	0.45*	0.24-.0.84	0.43*	0.29-0.64	0.82	0.42-1.61
HER2	1.39	0.78-2.48	3.19*	1.67-6.08	2.39*	1.33-4.28	1.78	0.93-3.42	2.66*	1.76-4.03	0.89	0.54-1.48
OS/SS/RS	2.65*	1.82-3.86	2.33*	1.60-3.38	2.39*	1.83-3.13	3.10*	2.02-4.75	2.25*	1.71-2.95	3.51*	2.33-5.31
DFS/MFS/RFS	2.65*	1.54-4.57	2.04*	1.53-2.73	1.95*	1.33-2.85	2.36*	1.67-3.32	1.93*	1.41-2.65	2.68*	1.73-4.13
Parameter	Antibodies used in studies				Surgery situation of patients				Overall
	BD		Abcam		Surgery		NS/Partly
	OR/HR	95% CI	OR/HR	95% CI	OR/HR	95% CI	OR/HR	95% CI	OR/HR	95% CI	P	I 2
Tumor size	1.30*	1.06-1.60	1.05	0.38-2.93	-	-	-	-	1.29*	1.06-1.58	0.012	0.0%
LNM	1.34*	1.08-1.67	0.76	0.39-1.48	-	-	-	-	1.27*	1.03-1.56	0.024	0.0%
SBR grade	2.65*	1.73-4.08	1.27	0.63-2.56	-	-	-	-	2.39*	1.61-3.54	0.000	70.4%
ER	0.43*	0.35-0.52	0.43*	0.36-0.52	-	-	-	-	0.43*	0.36-0.52	0.000	42.3%
PR	0.54*	0.36-0.80	0.30*	0.15-0.57	-	-	-	-	0.50*	0.35-0.71	0.000	65.1%
HER2	1.85*	1.19-2.87	2.83	0.53-15.07	-	-	-	-	1.95*	1.29-2.95	0.002	65.5%
OS/SS/RS	-	-	-	-	2.87*	2.17-3.80	1.76*	1.06-2.91-	2.58*	2.05-3.23	0.000	38.0%
DFS/MFS/RFS	2.07*	1.60-2.69	4.60*	1.53-13.81	2.09*	1.60-2.75	2.72*	1.32-5.60	2.16*	1.68-2.79	0.000	0.0%

Ps. *means a significant difference.