Table 3.
IOW Mediation of the adolescent MTO treatment-asthma diagnosis association; direct and indirect effects.
| Mediator domains | Direct effect |
Indirect effect |
% Change |
N | ||||||
|---|---|---|---|---|---|---|---|---|---|---|
| b | SE | p | b | SE | p | % Changeb | LCI | UCI | ||
| Mental healtha | 0.2482 | 0.137 | 0.070 | −0.0047 | 0.031 | 0.882 | 1.9% | −126.3% | 130.1% | 2812 |
| Smoking | 0.2279 | 0.139 | 0.100 | −0.0141 | 0.029 | 0.623 | 6.6% | −908.6% | 921.8% | 2693 |
| Housing disarray | 0.2871 | 0.142 | 0.043 | −0.0200 | 0.031 | 0.520 | 7.5% | −61.4% | 76.4% | 2534 |
| Housing quality observed | 0.2389 | 0.132 | 0.070 | −0.0044 | 0.037 | 0.906 | 1.9% | −146.5% | 150.3% | 2575 |
| Housing quality adult report | 0.2686 | 0.135 | 0.047 | −0.0445 | 0.032 | 0.160 | 19.9% | −289.8% | 329.6% | 2727 |
| Housing hardship | 0.2270 | 0.129 | 0.078 | 0.0037 | 0.035 | 0.916 | −1.6% | −454.4% | 451.2% | 2684 |
| Housing mobility | 0.2702 | 0.142 | 0.056 | −0.0266 | 0.042 | 0.527 | 10.9% | −173.0% | 194.9% | 2812 |
We tested a model including generalized anxiety disorder as a mediator; results were similar, with a percent change of −1.4%.
% change indicates the % change from the total to the direct effect. Positive values indicate an increase, or a countervailing mediation effect, and negative values indicate a decrease, or mediation in the expected direction, in the direct effect compared to the total effect. The total effect of MTO treatment on asthma diagnosis was b(SE) = 0.244(0.131), p = 0.062.