Table 1.

Liver Laboratory Values in 71 Individuals with OTCD

Clinical Classification (N)	Ammonia μmol/L			ALT IU/L			AST IU/L			PT seconds			INR
	Mean	SD	Range	Mean	SD	Range	Mean	SD	Range	Mean	SD	Range	Mean	SD	Range
Neonatal Male (12)	1232	817.6	41.1, 2634	109	85.6	22, 256	151	151	25, 467	23	9.8	8.6, 37.6	2.48	1.64	0.9, 6.41
Severe (9)	202	92.1	106, 410	923	827.6	16, 2089	1063	1405	16, 4139	32	19.4	10.6, 63.7	2.92	1.64	1.0, 5.7
Moderate (12)	155	92.4	37.6, 332	331	467.1	13, 1223	137	236	11, 785	14.8	7.4	10.4, 34.9	1.48	0.62	1.0, 3.1
Mild (15)*	72.2	79.7	9, 297	102	187.6	10, 689	71.1	129	14, 519	13	2.4	10.4, 17.6	1.15	0.14	0.95, 1.4
Asymptomatic (22)	39	22.97	9, 104.5	19	10.04	11, 49	23	13.5	10, 62	12	1.8	10.1, 16.2	1.04	0.09	0.92, 1.27

^*One individual was classified as mild but did not survive the initial presentation, his values are not included here.

Normal values: Ammonia: < 50 μmol/L (< 80 μmol/L in Neonates ); ALT: 10 – 35 IU/L; AST: 15 – 40 IU/L; PT: 12.0 – 15.0 seconds; INR: < 1.5