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. Author manuscript; available in PMC: 2014 Jun 25.
Published in final edited form as: Biol Psychiatry. 2013 May 20;74(7):511–519. doi: 10.1016/j.biopsych.2013.04.012

Figure 3. ELK1 expression levels are associated with polymorphism of the OPRM1 gene.

Figure 3

(A) Heroin subjects carrying the G allele of the rs1799971 SNP have highest the ELK1 expression. Control A/A, N=13; Heroin A/A, N=22, Heroin G, N=10. (B) Genotype-dose effect evident for the rs2075572 SNP in controls and heroin subjects with ELK1 expression levels highest in C/C subjects in each respective group. Control: C/C and C/G, N= 8 and 5, respectively; Heroin: C/C, C/G and G/G, N=8, 10 and 15, respectively. Mean ± SEM. * p < 0.05, ** p < 0.01.