Table 2.
Summary of the minimum inhibitory concentrations (MICs) and minimum bactericidal concentrations (MBCs) of the three novel AMPs (bombinin, feleucin-BV1, and feleucin-BV2) described in this study. NA: not active. Haemolysis values are those effecting 100% lysis of red blood cells in 120 min.
| Peptides | MIC (mg/L) | MBC (mg/L) | Haemolysis (mg/L) | ||||
|---|---|---|---|---|---|---|---|
| S. aureus | E. coli | C. albicans | S. aureus | E. coli | C. albicans | Horse red cells | |
| Bombinin | 8 | 32 | 32 | 32 | 32 | 32 | 64 |
| Feleucin-BV1 | 256 | NA | NA | 256 | NA | NA | >512 |
| Feleucin-BV2 | 128 | NA | NA | 256 | NA | NA | >512 |