Table 2.
Comparison of different tools in miRNA detection
| CAP-miRSeq | omiRAS | miRTools2 | Novoalign | |
|---|---|---|---|---|
| Version | v1.1 | 12/2013 | v2 | 2.07.13 |
| Aligner | Bowtie | Bowtie | SOAP | Novoalign+ |
| Ref Genome | hg19 | hg19 | hg19 | hg19 |
| Time | 5 hrs | 12 hrs | Variable | 6 hrs |
| Memory | 4 GB | - | - | 10 G |
| Mature miRNA (> = 2) | 860 | 739 | 172 | 881 |
| Novel miRNA | 194 | NA* | 35 | No prediction |
| Correlation with other tools | - | 0.99 | 0.81 | 0.95 |
*NA–omiRAS requires at least two samples to run with differential expression analysis; however, it does not report novel miRNAs for each individual sample. +Novoalign is just an alignment toot and it does not perform miRNA prediction and quantification. omiRAS and miRTool2 are web based tools and no memory usage information is available.