Skip to main content
. 2014 Jun 9;15(1):450. doi: 10.1186/1471-2164-15-450

Figure 3.

Figure 3

Condition table and heat maps for transcription networks of E2F1. (a) The condition table and heat map for the association between E2F1 and the gene set ‘transcription activator activity (GO:0016563)’. Several targets exhibit clear activations across a number of virus treated HeLa cells. Seven genes, Bmp2, E2f3, Epc1, Fosl1, Mll5, Myc and Nr4a3 are chosen for validation using a ChIP assay. (b) The heat map for the association between E2F1 and the gene set ‘negative regulation of protein kinase activity (GO:0006469)’. A part of the 55 conditions that associate E2F1 and the GO gene set are shown. Among the targets, Gadd45b and Dusp6 exhibit clear expression changes across a variety of microarray conditions. Both genes are tested using a ChIP assay.