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A. Cross-sectional aortic wall thickness (mean±SE) in micrometers2 in four treatment groups. B. Normalized internal diameter for aortic cross-sections, suggesting an eccentric remodeling in the Nic + ANG II group. Combined treatment of Nic + ANG II was the only permutation that significantly drove aortic hypertrophy. C. Representative images at 10× and 40× are shown for each group.
